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Department of Medical Biology

Department of Medical Biology

Our department was established on 30rd September 1998, as Mersin University Faculty of Medicine Department of Medical Biology and Genetics, with the appointment of Assist.Prof.Etem AKBAŞ. Assist.Prof.Nurcan ARAS ATEŞ was appointed on 23rd September 1999, Prof.Dr.Ali MATUR on 12th November 1999,  and M. Emin ERDAL was appointed on 22nd February 2000. Assist.Prof. İ.Ömer BARLAS on 15th September 2005, Assist.Prof. Mustafa Ertan AY and Assist.Prof. Özlem İZCİ AY on 4th October 2006 were appointed. The Master degree Program was opened in 1999 and the Doctorate Program in 2002. Our department is still; 6 faculty members, 2 research assistants, 1 biologist (Phd) and 1 technician in Mersin University Çiftlikköy Campus, Faculty of Medicine, Department of Basic Medical Sciences.

Mission:

Our department mission; is to bring together and integrate molecular genetics and clinical genetics research services. In line with this mission; In our department, we aim to develop new diagnosis and treatment methods on the genetic disorders by determining molecular pathogenesis of the genes that regulate the intracellular molecular pathways, and other molecular structures that regulate the functions of these genes, and chromosomes. Many basic and applied studies including molecular genetic changes in the etiology of cancer types and single gene diseases, are carried out in our department.

Vision:

Our department vision; To train students who can reflect the concept of molecular medicine to their professional practice and basic cellular and molecular genetic knowledge in all departments we teach (Faculty of Medicine, Faculty of Dentistry and Postgraduate Programs)

Technology Opportunities

Medical Biology Department routine, research, and student laboratories have progressed rapidly since its inception. Today, Medical Biology Department Laboratories have the advanced equipment necessary for all kinds of research and examination, especially routine patient services and thesis researches in the field of Medical Biology and Genetics. When needed; the equipments and technical facilities in Mersin University Advanced Technology, Education, Research and Application Center are also used.

Research Areas:

Mutation / genetic polymorphism analysis, gene expression studies, detection of irregularities in epigenetic mechanisms (miRNA analysis, methylation analysis, etc.) in inherited genetic diseases (single gene and multi-factorial genetic diseases) and acquired genetic diseases (cancer, etc.), Determination of the effects of environmental factors (radiation, radiofrequency waves, carcinogens, etc.) on diseases, cytogenetic analysis at the chromosomal level are the main research areas of our department.

According to the data of the year 2020 in the Web of Science database, there are approximately 200 SCI and SCI-E research publications addressed to our department. At the same time, there are papers and awards made in many international and national congresses.

Physical Facilities:

In our department; There are study offices for faculty members, research assistants and graduate students, a multi-purpose seminar room, 4 laboratories that provide research and routine laboratory services (Prenatal Genetic Diagnosis and Cell Culture Laboratory, Postnatal Genetic Diagnosis Laboratory, Cancer Cytogenetics Diagnostic Laboratory, Molecular Genetic Diagnosis Laboratory), and a student laboratory. In these laboratories, in addition to genetic analysis of samples from Mersin University Hospital and regional hospitals, many research projects are carried out at the level of cytogenetic and molecular genetics.

Information about Academic and Administrative Staff

Lecturers

Prof. Dr. Mehmet Emin ERDAL (Head of Department)

Prof. Dr. Nurcan ARAS

Prof. Dr. Etem AKBAŞ

Prof. Dr. İbrahim Ömer BARLAS

Assoc. Prof. Dr. Özlem İZCİ AY

Asst. Prof. Üyesi Mustafa Ertan AY

Research Assistants

Res.Assist. Duygu YOLAL ERTURAL

Res.Assist. Mehmet Tuğhan KIZILTUĞ (ÖYP, Teaching Staff Training Program)

Senior Biologist Fahri TURAN, PhD

Technician Firdevs BEDEL

Opportunities for Students

All physical areas of the Department of Medical Biology and Mersin University are available to students. Laboratories and devices are used for both thesis studies and other researches.

Post-Graduate Education Opportunities

Master’s Degree Program

The Department of Medical Biology has aimed to educate staff who can work in the field of health sciences and have gained basic laboratory skills with the Master’s program affiliated with the MEU Institute of Health Sciences. The department started to admit its first student in 2000. Students starting their graduate education, gain knowledge in the field of Medical Biology with theoretical lessons, practical trainings, discussions, oral presentations and article presentations and discussions and they graduate after completing a thesis study. As of 2020, there are 44 students who have graduated from our master's program with a master's degree.

MASTER’S DEGREE COURSES

COURSE CODE

MEDICAL BIOLOGY, (M.Sc.)

MEU CREDIT

ECTS

CREDIT

COMPULSORY COURSES

BIO 526

 

BASIC MEDICAL BIOLOGY AND GENETICS

(2+2) 3

8

BIO 524

 

SEMINAR

   (2+0) 0

4

BIO 528

 

SCIENTIFIC RESEARCH METHODS

(2+0) 0

4

BIO 600-5

 

SPECIALTY AREA

    (4+0) 4

        30

ELECTIVE COURSES

BIO 505

 

MEDICAL BIOLOGICAL TECHNIQUES

(2+2) 3

8

BIO 506

 

CYTOGENETIC

(2+2) 3

8

BIO 507

 

INTRODUCTION TO MOLECULAR BIOLOGY

(2+0) 2

4

BIO 508

 

MOLECULAR GENETICS I

(2+2) 3

8

BIO 509

 

MOLECULAR GENETICS II

(2+2) 3

8

BIO 510

MOLECULAR BIOLOGY OF CANCER

(2+0) 2

8

BIO 512

 

BIOLOGICAL CONTROL SYSTEMS

(2+0) 2

4

BIO 513

 

BIOLOGY AND GENETICS OF BACTERIA AND VIRUS

(3+0) 3

6

BIO 514

 

MUTATIONS AND MUTAGENS

(2+0) 2

4

BIO 515

 

GENOME ANALYSIS METHODS

(3+0) 3

6

BIO 517

 

HEREDITARY METABOLIC DISEASES

(2+2) 3

8

BIO 518

 

USAGE OF DNA ANALYSIS IN MEDICINE

(3+0) 3

6

BIO 520

 

PRENATAL DIAGNOSIS METHODS

(2+2) 3

8

BIO 521

 

LITERATURE SEARCHING IN MOLECULAR BIOLOGY

(1+0) 1

2

BIO 522

 

ARTICLE DISCUSSION

(1+0) 1

2

BIO 523

 

COMPUTER USAGE IN MEDICAL BIOLOGIC RESEARCHES

(1+0) 1

2

BIO 525

 

GENETICS OF FORENSIC MEDICINE

(2+2) 3

8

BIO 527

 

CYTOBIOLOGY

(3+0) 3

6


Doctorate Degree Program

The Department of Medical Biology aimed to educate instructors for Higher Education Institutions by gaining knowledge, experience and laboratory skills in the field of Medical Biology and Genetics, which can work in the field of Health Sciences with a PhD program affiliated to the MEU Institute of Health Sciences. Students who have successfully completed the "Doctoral Proficiency Exam", which is applied at the end of their theoretical and practical course, discussion, seminar and article presentation training, reach the level that they can carry out a thesis study in the field of Medical Biology. Students who successfully complete their thesis study are awarded with doctoral degree (PhD) and graduate. As of 2020, there are 17 students who have graduated from our doctorate program with a Ph.D degree.

DOCTORATE DEGREE COURSES

COURSE CODE

MEDICAL BIOLOGY, (PhD)

MEU CREDIT

ECTS

CREDIT

COMPULSORY COURSES

BIO 618

ADVANCED MOLECULAR GENETICS

(3+0) 3

 

10

BIO 624

 

SEMINAR

   (2+0) 0

4

BIO 600-5

 

SPECIALTY AREA

(4+0) 4

30

ELECTIVE COURSES

BIO 603

 

CANCER GENETICS

(2+0) 2

8

BIO 604

 

CHEMICAL STRUCTURE OF BODY FLUIDS AND ITS EXAMINATION

(2+2) 3

8

BIO 605

 

AUTOSOMAL DOMINANT AND RECESSIVE SYNDROMES

(2+2) 3

8

BIO 606

 

GONOSOMAL DOMINANT AND RECESSIVE SYNDROMES

(2+2) 3

8

BIO 608

 

MOLECULAR GENETICS CONCEPTS

(2+0) 2

6

BIO 609

 

METABOLIC REACTIONS IN THE CELL

(2+0) 2

6

BIO 610

 

GENETIC POLYMORPHISM

(1+2) 2

6

BIO 611

 

PRENATAL DIAGNOSIS AND GENETIC COUNSELING

(2+2) 3

10

BIO 613

 

PHARMACOGENETICS

(2+0) 2

6

BIO 616

 

CELLULAR CONTROL AND SIGNAL TRANSDUCTION

(3+0) 3

8

BIO 617

 

CELL CULTURE APPLICATIONS

(2+2) 3

8

BIO 619

 

ADVANCED CYTOGENETICS

(2+2) 3

10

BIO 620

 

BASIC MEDICAL GENETICS

(3+0) 3

8

BIO 621

 

MOLECULAR IMMUNOLOGY

(2+0) 2

6

BIO 622

 

USAGE OF RECOMBINANT TECHNOLOGY IN THERAPY

(3+0) 3

8

BIO 623

 

GENETIC ENGINEERING

(2+0) 2

6

 

      


Publications in International Scientific Journals(last two years)

2022
19. Zeybek, A.; öz, N.; Kalemci, S.; Tosun, K.; Edgünlü, T.; Kızıltuğ, M.; Tekin, L.; Erdal, M. . MOLECULAR BIOLOGY REPORTS, 2022, 49, 9-17.
10.1007/s11033-021-06759-2
2021
18. Karabulut, Y.; Bozkurt, F.; Türsen, .; Bayram, G.; Temel, G.; Erdal, M. The role of CD1a expression in the diagnosis of cutaneous leishmaniasis, its relationship with leishmania species and clinicopathological features.. DERMATOLOGIC THERAPY, 2021, 34, 1-9.
http://dx.doi.org/10.1111/dth.14977
17. Eras, N.; Celik, Y. Nonlethal Raine Syndrome in a Newborn Boy Caused by a Novel FAM20C Variant. MOL SYNDROMOL , 2021, 12, 169-173.
https://pubmed.ncbi.nlm.nih.gov/34177433/
16. Güvener, O.; Sezgin, M.; Tezol, .; Barlas, .; özdemir, A.; Kanık, E. . TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION, 2021, 67, 242-249.
10.5606/tftrd.2021.5481
15. Bayyurt, B.; Bakir, M.; Engin, A.; öksüz, C.; Arslan, S. Investigation of NEAT1, IFNG‐AS1, and NRIR expression in Crimean–Congo hemorrhagic fever. JOURNAL OF MEDICAL VIROLOGY, 2021, 93, 3300-3304.
http://dx.doi.org/10.1002/jmv.26606
14. Arslan, S.; Bayyurt, B.; Engin, A.; Bakır, M. MicroRNA Analysis from Acute to Convalescence in Crimean Congo Hemorrhagic Fever. JOURNAL OF MEDICAL VIROLOGY, 2021, 93, 4729-4737.
13. Görür, K.; Büyükafşar, K.; Akbaş, E.; Ismi, O.; Yolal ertural, D.; çetinkaya, A.; özcan, C. . J INT ADV OTOL, 2021, 16, 530-535.
10.5152/iao.2021.21132
12. Kara, H.; Erdal, M.; Yılmaz, S.; şengül, C.; şengül, C.; Karakülah, K. Association of NRG3 and ERBB4 gene polymorphism with nicotine dependence in Turkish population. MOLECULAR BIOLOGY REPORTS, 2021, 48, 5319-5326.
http://dx.doi.org/10.1007/s11033-021-06548-x
11. Eras, N.; Türköz, G.; Tombak, A.; Tiftik, E.; Yalın, S.; Berköz, M.; Erden, S.; Akbaş, E. . ARCHIVES OF MEDICAL SCIENCE, 2021, 17, 928-933.
10.5114/aoms.2019.89692
10. Eras, N.; Türköz, G.; Tombak, A.; Tiftik, E.; Yalın, S.; Berköz, M.; Akbaş, E.; Erden, S. . ARCHIVES OF MEDICAL SCIENCE, 2021, 4, 928-933.
10.5114/aoms.2019.89692
9. Arslan, S.; Tüzemen bayyurt, E.; Engin, A.; Bakır, M. . JOURNAL OF MEDICAL VIROLOGY, 2021, 93, -.
10.1002/jmv.26909
8. Güler kara, H.; Erdal, M.; Görücü yılmaz, .; şengül, C.; Balcı şengül, M.; Karakülah, K. . MOLECULAR BIOLOGY REPORTS, 2021, , -.
10.1007/s11033-021-06548-x
2020
7. Bahar, L.; Sucu, N.; Eras, N.; Bagdatoglu, O.; Yildirim, M. Adrenomedullin expression in aortic artery wall of diabetic rats given alpha lipoic acid. PHARMACOLOGICAL REPORTS, 2020, 1, 1-8.
http://dx.doi.org/10.1007/s43440-020-00082-6
6. Eras, N. A Case of Ring Chromosome 18 with Single Umbilical Artery Detected During Prenatal Period. MOLECULAR SYNDROMOLOGY, 2020, 11, 217-222.
http://dx.doi.org/10.1159/000509646
5. Erdal, M.; Görücü yılmaz, .; Ay, M.; Gür kara, H.; Avcı özge, A.; Taşdelen, B. A Study Investigating the Role of 2 Candidate SNPs in Bax and Bcl-2 Genes in Alzheimer’s Disease. PUERTO RICO HEALTH SCIENCES JOURNAL, 2020, 39, 264-269.
Publications_002.pdf
4. Böğrekci, G.; çetinkaya, A.; Kandemir, F.; Bekalp yılmaz, .; Orekici temel, G.; Aras, N. . MIKROBIYOLOJI BULTENI, 2020, 54, 279-290.
3. Erdal, M.; Karababa, .; Erdal, .; Basmacı kandemir, .; fries, G.; Bayazıt, H.; Ay, M.; Kandemir, H.; ızci ay, . MicroRNA dysregulation in manic and euthymic patients with bipolar disorder. JOURNAL OF AFFECTIVE DISORDERS, 2020, 261, 84-90.
10.1016/j.jad.2019.09.060
2. Bahar, L.; Sucu, N.; Eras, N.; Bagdatoglu, O.; Yıldırım, M. . PHARMACOLOGICAL REPORTS, 2020, 72, 912-921.
10.1007/s43440-020-00082-6
1. Tüzemen bayyurt, E.; Engin, A.; Bakır, M.; Arslan, S. . JOURNAL OF MEDICAL VIROLOGY, 2020, 93, -.
10.1002/jmv.26606