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Stem Cell and Regenerative Medicine Department

MISSION AND VISION

Mersin University Stem Cell and Regenerative Medicine Department aims to better understand the subjects related to stem and precursor cells with Tissue and Cell Production practices. Taking advantage of the extraordinary potential of stem cells, our department aims to continue research (experimental and clinical studies, basic sciences, tissue engineering), production (cell and cell products in clinical standards), education and consultancy activities at national and international levels. In addition, it aims to prepare the ground for the application of advanced regenerative medicine methods in the treatment of human diseases by observing medicine and ethical values. Mersin University Stem Cell and Regenerative Medicine Department also aims to be a regional power in stem cell transplantation and stem cell research. In addition to genetic disorders, cancer treatments and blood diseases, it is our main goal to be an active and leader in many disciplines such as neurology, cardiology, orthopedics, endocrinology, dermatology, plastic and reconstructive surgery, pharmacogenetics and biotechnological studies. In the production of human-derived cells; It is aimed to develop "Biotechnological drugs and methods" with Good Manufacturing Conditions (GMP) and Good Laboratory Conditions (GLP).


Publications in International Scientific Journals(last two years)

2022
60. Demir, D.; özdemir, S.; Ceylan, S.; Yalcin, M.; Sakım, B.; Bölgen, N. Electrospun Composite Nanofibers Based on Poly (ε-Caprolactone) and Styrax Liquidus (Liquidambar orientalis Miller) as a Wound Dressing: Preparation, Characterization, Biological and Cytocompatibility Results. JOURNAL OF POLYMERS AND THE ENVIRONMENT, 2022, Published online, 1-12.
http://dx.doi.org/10.1007/s10924-022-02376-7
59. çekiç, D.; Yılmaz, .; Bölgen, N.; ünal, S.; Duce, M.; Bayrak, G.; Demir, D.; Türkegün, M.; Sarı, A. Impact of injectable chitosan cryogel microspherescaffolds on differentiation and proliferation of adiposederived mesenchymal stem cells into fat cells. JOURNAL OF BIOMATERIALS APPLICATIONS, 2022, 36, 1335-1345.
http://dx.doi.org/10.1177/08853282211048284
58. Picillo, M. Uncovering clinical and radiological asymmetry in progressive supranuclear palsy-Richardson's syndrome. NEUROLOGICAL SCIENCES, 2022, 43, 3677-3682.
https://pubmed.ncbi.nlm.nih.gov/35106692//
57. Demir, D.; özdemir, S.; Gonca, S.; Bölgen, N. Novel styrax liquidus loaded chitosan/polyvinyl alcohol cryogels with antioxidant and antimicrobial properties. JOURNAL OF APPLIED POLYMER SCIENCE, 2022, 139, 52033-52033.
http://dx.doi.org/10.1002/app.52033
56. Erdem kış, E.; Tiftik, R.; Al hennawı, K.; ün, . . MOLECULAR BIOLOGY REPORTS, 2022, , -.
10.1007/s11033-022-07546-3
2021
55. Dündar, A.; Kocahan, S.; şahin, L. . ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2021, , 1-5.
10.1080/13813455.2019.1635622
54. Saylam, B.; Efesoy, O.; Bozdoğan arpacı, R.; Tiftik, R.; Tek, M.; Büyükafşar, K.; Bozlu, M.; çayan, S. . TURKISH JOURNAL OF MEDICAL SCIENCES, 2021, 49, 1491-1499.
10.3906/sag-2004-15
53. Saylam, B.; Efesoy, O.; Bozdoğan arpacı, R.; Tiftik, R.; Tek, M.; Büyükafşar, K.; Bozlu, M.; çayan, S. . TURKISH JOURNAL OF MEDICAL SCIENCES, 2021, 51, 1491-1499.
10.3906/sag-2004-15
52. Eras, N.; Celik, Y. Nonlethal Raine Syndrome in a Newborn Boy Caused by a Novel FAM20C Variant. MOL SYNDROMOL , 2021, 12, 169-173.
https://pubmed.ncbi.nlm.nih.gov/34177433/
51. Berköz , M.; Yıldırım , M.; Bahar , L.; Sucu , N.; ılhan, .; Yalın, . The Protectıve Effect Of Alpha Lıpoıc Acıd On Retınal Damage In Streptozotocın-Induced Dıabetıc Rats. FRESENIUS ENVIRONMENTAL BULLETIN, 2021, 30, 24-33.
file:///C:/Users/Leyla/Downloads/FEB_07A_2021_Pp_08818-09635%20(4).pdf
50. Tiftik, E. . CLINICAL LABORATORY, 2021, 67, 2700-2706.
10.7754/Clin.Lab.2021.210324)
49. Duman, .; Tiftik, R.; ün, . . NUTRITION AND CANCER, 2021, 73, 273-281.
10.1080/01635581.2020.1764066
48. Alakaya, M.; Kaya, S.; Arslanköylü, A.; Tezol, .; Karhan, A.; Tiftik, E. . TURKISH JOURNAL OF PEDIATRIC DISEASE, 2021, 15, 294-298.
10.12956/tchd.715777
47. Ilhan, E.; Büyükafşar, K.; Tiftik, R.; Seçilmiş, M.; Alzayed, Z. . BALKAN MEDICAL JOURNAL, 2021, 38, 304-309.
10.5152/balkanmedj.2021.20014
46. Tiftik, R.; Temiz reşitoğlu, M.; Güden, D.; Bayrak, G.; ün, .; Yılmaz, .; şahan fırat, S. . CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021, 99, 418-426.
10.1139/cjpp-2020-0305
45. Koyuncu, M.; Köşeci, T.; Güler, E.; Ten, B.; Apaydın, F.; Nayır, E.; Basır, H.; Akdeniz, A.; Tombak, A. . TURKISH JOURNAL OF GERIATRICS, 2021, 24, 518-525.
10.31086/tjgeri.2021.249
44. Tiftik, E. . EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2021, 25, 6557-6565.
10.26355/eurrev_202111_27126
43. Hazır, S.; Yıldırım yaroglu, H.; Bayram, G.; Askın, A. NVESTIGATION OF THE POSSIBLE ROLE OF POLY (ADP-RIBOSE) POLYMERASE PATHWAY IN NICOTINE- EXPOSED TESTICULAR DAMAGE. . FRESENIUS ENVIRONMENTAL BULLETIN, 2021, 30, 7542-7550.
Publications_042.pdf
42. Hazır, S.; Yıldırım yaroğlu, H.; Bayram, G.; Aşkın, A. . FRESENIUS ENVIRONMENTAL BULLETIN, 2021, , 7542-7550.
41. Sezgin, O.; Yaraş, S.; Tezcan ülger, S.; Aslan, G.; Tiftik, E. . TURKISH JOURNAL OF GASTROENTEROLOGY, 2021, 32, 782-789.
10.5152/tjg.2021.20870
40. Berköz, M.; Yıldırım, M.; Bahar, L.; Sucu, N.; Ilhan, M.; Yalın, A. . FRESENIUS ENVIRONMENTAL BULLETIN, 2021, 30, 8824-8833.
39. Yıldırım yaroğlu, H.; Akbayır, S.; Görür, A.; Balcı fidancı, .; ünal, Z.; Ayaz, L.; Ayan, E.; Tamer, L. . FRESENIUS ENVIRONMENTAL BULLETIN, 2021, 30, 9107-9113.
38. Eras, N.; Türköz, G.; Tombak, A.; Tiftik, E.; Yalın, S.; Berköz, M.; Akbaş, E.; Erden, S. . ARCHIVES OF MEDICAL SCIENCE, 2021, 4, 928-933.
10.5114/aoms.2019.89692
37. Saleh, M.; Demir karakuş, D.; özay, Y.; Yalvaç, M.; Karagülle, N.; Dizge, N. . JOURNAL OF APPLIED POLYMER SCIENCE, 2021, 138, -.
10.1002/app.50599
36. Vega-adauy, J.; özden tok, .; çelik, A.; Barutçu, A.; Vannan, M. . HEART FAILURE CLINICS, 2021, 17, -.
10.1016/j.hfc.2021.03.006
35. şahin, L.; çevik, .; çevik, K.; Güven, C.; Taşkın güven, E.; Kocahan, S. . BRAIN RESEARCH, 2021, 1759, -.
10.1016/j.brainres.2021.147367
34. Köse, A.; çelik, A.; Altınsoy, E.; Bozkurt babuş, S.; Erdoğan, S. . CARDIOVASCULAR TOXICOLOGY, 2021, 21, -.
10.1007/s12012-020-09594-2
33. çelik, A. . NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384, -.
10.1056/NEJMoa2025797
32. çelik, A. . THE LANCET, 2021, 398, -.
10.1016/S0140-6736(21)01122-3
31. Ayaz, F.; Demir karakuş, D.; Karagülle, N. . ARTIFICIAL CELLS, NANOMEDICINE, AND BIOTECHNOLOGY, 2021, 49, -.
10.1080/21691401.2021.2012184
30. Ayaz, F.; Demir karakuş, D.; Karagülle, N. . JOURNAL OF MATERIALS SCIENCE, 2021, 56, -.
10.1007/s10853-021-06399-8
29. çelik, A. . JAMA CARDIOLOGY, 2021, 6, -.
10.1001/jamacardio.2020.6455
28. Kaya, H.; şahin, A.; Bekar, L.; çelik, A.; çavuşoğlu, Y.; çaldır, M.; Güngör, H.; Yılmaz, M. . ACTA CARDIOLOGICA, 2021, 76, -.
10.1080/00015385.2020.1797303
27. çelik, A. . ESC HEART FAILURE, 2021, 8, -.
10.1002/ehf2.13549
26. Kocahan, S.; Akıllıoğlu, K.; Sencar, L.; şahin, L.; çevik, .; Taşkın güven, E.; Güven, C.; Boğa pekmezekmek, A.; Polat, S. . INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 2021, 81, -.
10.1002/jdn.10142
25. Kaya, H.; şahin, A.; Güneş, H.; Bekar, L.; çelik, A.; çavuşoğlu, Y.; çaldır, V.; Güngör, H.; Yılmaz, M. . ACTA CARDIOLOGICA, 2021, , -.
10.1080/00015385.2020.1797303
2020
24. Köse, A.; çelik, A.; Altınsoy, E.; Bozkurt babus, S.; Erdoğan, S. The Effect of Emergency Department Visits and Inflammatory Markers on One-Year Mortality in Patients with Heart Failure. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 0-0.
http://dx.doi.org/10.1007/s12012-020-09594-2
23. Kırbıyık, I.; özçimen, A. . JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2020, 0, 0-.
10.4103/jcrt.JCRT_827_19
22. Shah hosseini, N.; Khenoussi, N.; Karagülle, N.; Ceylan, S.; Göktürk, D.; Schacher, L.; Adolphe, D.; Tamayol, A. . INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, 2020, , 1-10.
21. öksüz, N. . MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2020, 42, 1-7.
10.1016/j.msard.2020.102055
20. Tüysüz, M.; Bahar, L. . BRAZILIAN JOURNAL OF CARDIOVASCULAR SURGERY, 2020, 35, 1-8.
10.21470/1678-9741-2019-0470
19. Kaya, H.; şahin, A.; Güneş, H.; Bekar, L.; çelik, A.; çavuşoğlu, Y.; çaldır, V.; Güngör, H.; Yılmaz, M. Increased frequency of occurrence of bendopnea is associated with poor outcomes in heart failure outpatients. INFORMA UK LIMITED, 2020, 1-9.
http://dx.doi.org/10.1080/00015385.2020.1797303
18. Bahar, L.; Gül, M.; Reşitoğlu, B.; çelik, Y.; Erden, S.; Gül, S. The Effects of Fibroblast Growth Factor-2 and Ozone Therapy on Acute Kıdney Injury in Renal Ischemıa/Reperfusıon Injury. FRESENIUS ENVIRONMENTAL BULLETIN, 2020, 29, 11143-11150.
Publications_003.pdf
17. Altay, B.; Dede, E.; özgül, .; Atıl, F.; Koçyiğit, .; Orhan, K.; Tekin, U.; Korkusuz, P.; önder, M. . JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2020, 78, 1171-1182.
16. Karagülle, N.; Demir, D.; Yalçın, M.; özdemir, S. . INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 161, 1581-1590.
15. Tiftik, E. . CLINICAL LABORATORY, 2020, 66, 1709-1715.
10.7754/Clin.Lab.2020.191218.
14. çelik, A. . NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382, 1883-1893.
13. Eras, N. . MOLECULAR SYNDROMOLOGY, 2020, 11, 217-222.
10.1159/000509646
12. Kayhan kuştepe, E.; Bahar, L.; Zayman, E.; Sucu, N.; Gül, S.; Gül, M. . BIOTECHNIC HISTOCHEMISTRY, 2020, 95, 305-316.
10.1080/10520295.2019.1695942
11. çavuşoğlu, Y.; Altay, H.; Cahn, A.; çelik, A.; Demir, .; Kılıçaslan, B.; Nalbantgil, S.; Raz, I.; Temizhan, A. Sodium Glucose Co-transporter 2 Inhibitors in Heart Failure Therapy. TURKISH SOCIETY OF CARDIOLOGY, 2020, 48, 330-354.
http://dx.doi.org/10.5543/tkda.2020.74332
10. Güngör, H.; Kaman, S.; özgül, .; önder, M.; Atıl, F.; Tekin, U.; Koçyiğit, . . JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, 2020, 10, 336-340.
9. Uyar, H.; Yesil, E.; Karadeniz, M.; örsçelik, .; özkan, B.; özcan, .; çiçek yılmaz, D.; çelik, A. The Effect of High Lactate Level on Mortality in Acute Heart Failure Patients With Reduced Ejection Fraction Without Cardiogenic Shock. CARDIOVASCULAR TOXICOLOGY, 2020, 20, 361-369.
8. Demir, D.; Ceylan, S.; Atakav, Y.; Karagülle, N. . INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION, 2020, 25, 421-430.
7. öfkeli, F.; Demir, D.; Karagülle, N. . JOURNAL OF APPLIED POLYMER SCIENCE, 2020, , 50337-.
6. Bahar, L.; Tüysüz, M. . BRATISLAVA MEDICAL JOURNAL, 2020, 121, 516-521.
10.4149/BLL_2020_085
5. Tüysüz, M.; Bahar, L. . BRAZILIAN JOURNAL OF CARDIOVASCULAR SURGERY, 2020, 35, 675-682.
10.21470/1678-9741-2019-0470
4. Güngör, A.; Demir, D.; Karagülle, N.; özdemir, T.; Genç altürk, R. . INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, 2020, 70, 810-819.
10.1080/00914037.2020.1765355
3. Bahar, L.; Sucu, N.; Eras, N.; Bagdatoglu, O.; Yıldırım, M. . PHARMACOLOGICAL REPORTS, 2020, 72, 912-921.
10.1007/s43440-020-00082-6
2. Ozden tok, O.; çelik, A. . CIRCULATION-CARDIOVASCULAR IMAGING, 2020, 13, -.
1. çelik, A.; Aksakal, E.; Aksu, U.; Altay, H.; Yıldırım, N.; çelik, A.; Akıl, M.; Bekar, L.; Vural, M. Snapshot Evaluation of Acute and Chronic Heart Failure in Real Life in Turkey: Follow up data for mortality. ANATOLIAN JOURNAL OF CARDIOLOGY, 2020, , -.
10.14744/AnatolJCardiol.2019.87894